Jan 10-15, 2016
Trapp Family Lodge
700 Trapp Hill Rd
Stowe, VT 05672
Telephone: (802) 760-6325, (800) 826-7000
Lectures & Pset sessions:
Mozart room
Poster sessions:
St. George’s Hall
Breakfast:
Dining Room
Dinner:
St. George’s Hall or Dining Room
Social Hour:
Lounge and Sunroom
Coffee:
Hallways
Lunch:
On your own
Sunday, January 10, 2016
| 2:00 – 5:30 pm 5:30 – 7:00 pm 7:00 – 8:15 pm 8:30 – 10:00 pm | Reception, front desk Buffet dinner, St George’s Hall Mei Hong Social hour | Welcome and introduction to basic theory of SSNMR |
Monday, January 11, 2016
| 7:00 – 8:00 am 7:30 – 8:00 am 8:00 – 9:30 am 9:30 – 10:00 am 10:00 – 11:30 am 11:30 am – 2:00 pm 2:00 – 4:00 pm 4:00 – 5:30 pm 5:30 – 7:00 pm 7:00 – 8:30 pm 8:30 – 9:30 pm 9:30 – 10:30 pm | Breakfast Poster setup, St George’s Hall Leonoard Mueller Coffee Christopher Jaroniec LunchFree time Vladmir Ladizhansky Buffet dinner, Dining Room Robert Griffin Poster session #1 Leonard Mueller | Manipulations in Spin and Space Heteronuclear dipolar recoupling and AHT Multidimensional correlation techniques for resonance assignment & structure determination Dynamic nuclear polarization (PT and DNP notes) Problem set session #1 |
Tuesday, January 12, 2016
| 7:00 – 8:00 am 8:00 – 9:30 am 9:30 – 10:00 am 10:00 – 11:30 am 11:30 am – 2:00 pm 2:00 – 4:00 pm 4:00 – 5:30 pm 5:30 – 7:00 pm 7:00 – 8:30 pm 8:30 – 9:30 pm 9:30 – 10:30 pm | Breakfast Mei Hong Coffee Bernd ReifLunch Free time David Rovnyak Buffet dinner, St. George’s Hall Ann McDermott Robert Griffin Social Hour | Molecular dynamics from solid-state NMR & basic phase cycling 1H detection techniques and paramagnetic NMR Non-uniform sampling Intermediate exchange Homonuclear dipolar recoupling |
Wednesday, January 13, 2016
| 7:00 – 8:00 am 8:00 – 9:30 am 9:30 – 10:00 am 10:00 – 11:30 am 11:30 am – 2:00 pm 2:00 – 4:00 pm 4:00 – 5:30 pm 5:30 – 7:00 pm 7:00 – 8:30 pm 8:30 – 10:00 pm | Breakfast Tim Cross Coffee Philip Grandinetti Lunch Charles Schwieters Charles Schwieters Buffet dinner, Dining Room Stanley Opella Poster session #2 | Oriented-membrane SSNMR I SSNMR of quadrupolar nuclei XPLOR-NIH (Installation Instructions) Hands-on XPLOR-NIH workshop Oriented-membrane SSNMR II (Mei Hong’s Notes) |
Thursday, January 14, 2016
| 7:00 – 8:00 am 8:00 – 9:30 am 9:30 – 10:00 am 10:00 – 11:30 am 11:30 am – 2:00 pm 2:00 – 3:00 pm 3:00 – 4:00 pm 4:00 – 5:30 pm 7:00 – 9:00 pm 9:00 – 10:00 pm | Breakfast Reif, McDermott Coffee Jaroniec, Hong Lunch David Rovnyak Coffee Opella, Cross Banquet, St. George’s Hall Social Hour | Advanced topics: Reif, McDermott Advanced topics: Jaroniec, Hong Problem set session #2 Advanced topics: Opella, Cross Pt. I, Cross Pt. II |
Friday, January 15, 2016
| 7:00 – 8:00 am 8:00 – 9:30 am 9:30 – 10:00 am 10:00 – 11:30 am 11:30 – 11:45 am | Breakfast Mueller, Ladizhansky Coffee Griffin, Grandinetti Jaroniec, Hong | Advanced topics: Mueller, Ladizhansky Advanced topics: Griffin, Grandinetti Closing remarks |
The 4th U.S.-Canada Winter School on Biomolecular Solid-State NMR
| Dates January 10-15, 2016 | Organizers Mei Hong (MIT) Chris Jaroniec (Ohio State) |
| Location Trapp Family Lodge 700 Trapp Hill Rd Stowe, VT 05672 Telephone: (800) 826-7000 |
The 4th Winter School on Biomolecular Solid-State NMR will be held on January 10-15, 2016, in Stowe, Vermont. Similar to the three previous highly successful Winter Schools, this pedagogical meeting is aimed at students and postdocs in solid-state NMR as well as more senior scientists in related fields who are interested in entering this vibrant field. Our goals are to provide a focused week of teaching of the core concepts and practices in the increasingly multifaceted and complex field of biological solid-state NMR spectroscopy, and to encourage information sharing among different laboratories.
Scope
- Basics of solid-state NMR: orientation-dependent NMR frequencies, MAS, tensors and rotations, density operator and its time evolution, dipolar recoupling, and average Hamiltonian theory.
- Multidimensional correlation spectroscopy, resonance assignment and protein structure determination
- Theory of dipolar decoupling and polarization transfer
- Pushing the sensitivity envelope: dynamic nuclear polarization and 1H detection
- Effective “sensitivity enhancement” by non-uniform sampling
- Solid-state NMR techniques for measuring molecular motion
- Solid-state NMR techniques for measuring membrane protein orientation
- Beyond spin 1/2: NMR of quadrupolar nuclei
- Beating the 800-pound gorilla: NMR of membrane proteins
- XPLOR-NIH for structure calculation
Confirmed Speakers
- Tim Cross (Florida State University)
- Philip Grandinetti (Ohio State University)
- Bob Griffin (MIT)
- Mei Hong (MIT)
- Chris Jaroniec (Ohio State University)
- Vladimir Ladizhansky (University of Guelph)
- Ann McDermott (Columbia University)
- Len Mueller (UC Riverside)
- Stanley Opella (UC San Diego)
- Bernd Reif (Technical University of Munich)
- David Rovnyak (Bucknell University)
- Charles Schwieters (NIH)
Registration
The registration fee is $425 for academic attendees and $600 for industrial attendees. Please send a check, made payable to “MIT”, for the registration fee to the following person and address:
Sara Frenier
Department of Chemistry
Bldg 18-281
Massachusetts Institute of Technology
77 Massachusetts Avenue
Cambridge, MA 02139
Email: saraf@mit.edu
Sponsors
