The 4th U.S.-Canada Winter School on Biomolecular Solid-State NMR

Link to 2018 Winter School Website

January 10-15, 2016
700 Trapp Hill Rd 
Stowe, VT 05672
Telephone: (800) 826-7000

        The 4th Winter School on Biomolecular Solid-State NMR will be held on January 10-15, 2016, in Stowe, Vermont. Similar to the three previous highly successful Winter Schools, this pedagogical meeting is aimed at students and postdocs in solid-state NMR as well as more senior scientists in related fields who are interested in entering this vibrant field. Our goals are to provide a focused week of teaching of the core concepts and practices in the increasingly multifaceted and complex field of biological solid-state NMR spectroscopy, and to encourage information sharing among different laboratories.

  • Basics of solid-state NMR: orientation-dependent NMR frequencies, MAS, tensors and rotations, density operator and its time evolution, dipolar recoupling, and average Hamiltonian theory.
  • Multidimensional correlation spectroscopy, resonance assignment and protein structure determination
  • Theory of dipolar decoupling and polarization transfer
  • Pushing the sensitivity envelope: dynamic nuclear polarization and 1H detection
  • Effective "sensitivity enhancement" by non-uniform sampling
  • Solid-state NMR techniques for measuring molecular motion
  • Solid-state NMR techniques for measuring membrane protein orientation
  • Beyond spin 1/2: NMR of quadrupolar nuclei
  • Beating the 800-pound gorilla: NMR of membrane proteins
  • XPLOR-NIH for structure calculation
Confirmed Speakers

         The registration fee is $425 for academic attendees and $600 for industrial attendees. Please send a check, made payable to "MIT", for the registration fee to the following person and address:

Sara Frenier
Department of Chemistry
Bldg 18-281
Massachusetts Institute of Technology
77 Massachusetts Avenue
Cambridge, MA  02139